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There is no way Post Date: Sat, 18 Oct 2008 9:55:36 +0000
The symptoms and therapy of acute iodine poi-soning are described in Chapter 50.Chronic iodide poisoning, or iodism, is much more common than acute iodide poisoning. There is no way of predicting which patient will react unfavor-ably, and an individual may vary in his sensitivity to the drug from time to time.
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Increased salivation is noted Post Date: Sat, 18 Oct 2008 9:41:25 +0000
Eventually, iodism will occur in all individuals if the dose is sufficiently high.The symptoms start with an unpleasant brassy taste and burning in the mouth and throat, as well as soreness of the teeth and gums. Increased salivation is noted.
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" The patient often complains Post Date: Sat, 18 Oct 2008 9:30:33 +0000
Coryza, sneezing, and irritation of the eyes with swelling of the eyelids are commonly observed. Mild iodism simulates a "head cold." The patient often complains of a severe headache that originates in the frontal sinuses.
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In addition, the parotid Post Date: Sat, 18 Oct 2008 9:12:07 +0000
Irritation of the mucous glands of the respiratory tract causes a productive cough. Excess transudation into the bronchial tree may lead to pulmonary edema. In addition, the parotid and submaxillary glands may become enlarged and tender, and the syndrome may be mistaken for mumps parotitis.
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They usually are mildly acneform Post Date: Sat, 18 Oct 2008 8:57:48 +0000
There also may be inflammation of the pharynx, larynx, and tonsils. Skin lesions are common, and vary in type and intensity. They usually are mildly acneform and distributed in the seborrheic areas.
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Symptoms of gastric irritation Post Date: Sat, 18 Oct 2008 8:41:04 +0000
Rarely, severe and sometimes fatal eruptions (ioderma) may occur after the prolonged use of iodides. The lesions are bizarre, resemble those caused by bromide, and, as a rule, involute quickly when iodide is withdrawn. Symptoms of gastric irritation are common; and diarrhea, which is sometimes bloody, may occur.
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Treatment of Iodism Post Date: Sat, 18 Oct 2008 8:23:09 +0000
Fever is occasionally observed, and anorexia and depression may be present. The mechanisms involved in the production of these derangements remain unknown.Treatment of Iodism.
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Abundant fluid and sodium chloride Post Date: Sat, 18 Oct 2008 8:05:56 +0000
Fortunately, the symptoms of iodism disappear spontaneously within a few days after stopping the administration of iodide. There-fore, treatment consists in withdrawing the offending medication and using supportive measures as deter-mined by the particular symptoms. Abundant fluid and sodium chloride intake may be of assistance in hastening iodide elimination.
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The preparations described below may Post Date: Sat, 18 Oct 2008 7:55:10 +0000
In severe cases, the establishment of an osmotic diuresis by the judicious use of mannitol may be advantageous.Preparations. The preparations described below may be grouped into three classes, as follows: (1) inorganic iodides, (2) organic compounds that yield the iodide ion, and (3) iodine-containing organic compounds that are used solely as contrast media in roentgenography.
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Hydriodic acid syrup (1,4% hydriodicacid) Post Date: Sat, 18 Oct 2008 7:43:14 +0000
Inorganic Iodides. The important inorganic iodide preparations (Potassium Iodide, USP, Potassium Iodide Solution, USP, Sodium Iodide, USP, and Strong Iodine Solution, USP) used in the treatment of thyroid disorders are described in Chapter 67. Hydriodic acid syrup (1,4% hydriodicacid) is used as a vehicle for many expectorant drugs.
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