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, 1963) Post Date: Fri, 17 Oct 2008 18:28:05 +0000
The degree of skeletal involvement varies from changes that are barely detectable radiologi-cally to marked thickening of the cortex of long bones, numerous exostoses scattered throughout the skeleton, and calcification of ligaments, tendons, and muscle attachments to bone. In its severest form it is a disabling disease and is designated as crippling fluorosis {see Singh et a!., 1963).
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In severe cases, discrete Post Date: Fri, 17 Oct 2008 18:17:09 +0000
Mottled enamel or dental fluorosis is a well-recognized entity that was first described over 50 years ago. The gross changes in very mild mottling consist in small, opaque, paper-white areas scattered irregularly over the tooth surface. In severe cases, discrete or confluent, deep brown- to black-stained pits give the tooth a corroded appearance.
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Since mottled enamel is a developmental Post Date: Fri, 17 Oct 2008 18:04:57 +0000
Mottled enamel is the result of a partial failure of the enamel-forming cells properly to elaborate and lay down enamel. It is a nonspecific response to a variety of stimuli, one of which is the ingestion of excessive amounts of fluoride.Since mottled enamel is a developmental injury, the ingestion of fluoride following the eruption of the tooth has no effect.
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Continuous use of water containing Post Date: Fri, 17 Oct 2008 17:45:51 +0000
Mottling is one of the first visible signs of an excessive intake of fluoride during childhood. A quantitative relationship between the fluoride concentration of drinking water and mot-tling has been demonstrated (Muhler and Hine, 1959). Continuous use of water containing about 1,0 ppm of fluoride may result in the very mildest form of mottled enamel in 10% of children.
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Experiments in con-trolling the fluoride Post Date: Fri, 17 Oct 2008 17:34:07 +0000
The incidence rises to 40 to 50% at about 1,7 ppm; at 2,5 ppm, it is as high as 80%, with 25% being classified as moderate or severe; between 4,0 and 6,0 ppm, the incidence approaches 100%, with marked increase in severity.Fluoride and Dental Caries. Experiments in con-trolling the fluoride content of water took an unex-pected and significant turn when it was observed that children born at Bauxite, Arkansas, after a new water supply had been obtained, showed a much higher incidence of caries than those who had been exposed to the former fluoride-containing water (Dean et al, 1941).
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The Society of Toxicology Post Date: Fri, 17 Oct 2008 17:16:51 +0000
This led to extensive studies on the part of the United States Public Health Service to ascertain whether the fluoridation of water could be employed as a practical measure to reduce the incidence of tooth decay. It has now been definitely established on the basis of large-scale studies in a number of communities that the fluoridation of water to a concentration of 1,0 ppm is a safe and practical public health measure that results in substantial reduction in the incidence of caries in per-manent teeth. The Society of Toxicology has studied the question of the safety of water fluoridation and has published the following statement (see Statement by the Society of Toxicology, 1969):From a critical review of the voluminous and steadily growing literature on the biological effects of inorganic fluoride no evidence has been found of an ill effect of water fluoridation at 1 ppm in temperate climates.
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Therefore, an extraordinary and exceptional Post Date: Fri, 17 Oct 2008 17:06:15 +0000
In the United States, there are over 10 million people drinking naturally fluoridated water at the near optimal concentration or higher. These waters have been consumed by large num-bers of people for many years. Therefore, an extraordinary and exceptional reliability is conferred on the safety of water fluoridation because nature, in a sense, has already made the demonstration in hundreds of communities where the drinking water naturally contains fluoride.
Autor of the post: Undefined
Topical applications of fluo-ride solutions Post Date: Fri, 17 Oct 2008 16:46:58 +0000
Under con-troUed conditions as recommended by qualified public health authorities, the Society of Toxicology finds water fluoridation to be a safe measure.There are partial benefits for children who begin drinking fluoridated water at any age; however, optimal benefits are obtained at ages before the permanent teeth erupt. Topical applications of fluo-ride solutions by dental personnel appear to be par-ticularly effective on newly erupted teeth and can reduce the incidence of caries by 30 to 40%.
Autor of the post: Undefined
Adequate incorporation of fluoride into teeth Post Date: Fri, 17 Oct 2008 16:29:09 +0000
The prescription of dietary fluoride supplements should be considered for children whose drinking water contains less than 0,7 ppm of fluoride. Conflicting results have been reported from studies of the effec-tiveness of fluoride-containing toothpastes.Adequate incorporation of fluoride into teeth causes the outer layers of enamel to be harder and more resistant to demineralization.
Autor of the post: Undefined
The mechanism of prevention Post Date: Fri, 17 Oct 2008 16:15:05 +0000
The deposition of fluoride ion appears to be an anion-exchange process with hydroxyl and/or citrate ions (Gedalia et al, 1969). The fluoride ion occupies the anionic spaces in the enamel apatite crystal surface. The mechanism of prevention of caries exerted by the deposition of minute amounts of fluoride in surface enamel is not completely understood.
Autor of the post: Undefined
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